I wasn't sure if he was only able to 'fix' her after realizing that the original brainscan was manufactured. But anyway, if he could have cured her in five years, why not cure her as soon as she came in and then get her consent? Adele refers to her before Topher even meets her as 'the new Sierra.' So basically she was totally okay with abducting a mental patient, keeping her mind in a box for an indefinite period of time, and renting out her body to anybody who wanted it. How, in Adele's eyes, is that justifiable, but what Sierra's stalker did isn't? (My theory on it is that, to Adele, exploiting people for science is justifiable, but exploiting people for your own pleasure/gain is reprehensible. So that's why I think the comment about her use of Victor hit a mark with her -- she genuinely feels guilty about using the Dollhouse to enjoy herself.)